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Extra12/12/2007 10:50 AM ET

5 stocks with great potential

The MSN CAPS community can help investors identify which companies among the thousands of pretenders might be tomorrow's top holdings.

By The Motley Fool

There always will be companies that are obviously great investments -- in hindsight.

Looking in the rearview mirror, we can see we should have bought Starbucks (SBUX, news, msgs) at its initial public offering and realized 1,000%-plus returns over the years.

Yet for every stock out there screaming "buy me," others simply give us a nudge in the ribs and a knowing nod. They may be tomorrow's obviously great investments, but how do we tell them from the thousands of pretenders?

Over on our CAPS investor-intelligence site, we know these opportunities as four-star stocks, companies that rank higher than most of the other 5,000 stocks in the CAPS universe but are just shy of achieving stardom. In the long shadows of stocks that garner the coveted five-star rating are top-tier companies approaching greatness.

While the full "secret sauce" of the way ratings are calculated is proprietary, three factors influence a stock's star rating:

  • Whether it's rated "outperform" or "underperform."

  • The length of time it is expected to perform (a few months or a few years).

  • The ratings of the investors who make the picks.

Every investor is rated just as every stock is rated. The best and brightest of these players are considered All-Stars. Because they are correct more consistently than their peers, their opinions weigh more heavily in favor of (or against) a stock.

So while all the attention might be focused on the five-star stocks, good four-star investments slip under the radar. A recent sift through the CAPS database in search of worthy companies approaching greatness uncovered five names:

Headed for greatness?
CompanyIndustryMarket capForward price-to-earnings ratio

Abbott Laboratories

Pharmaceuticals

$90 billion

20.8

Archer Daniels Midland

Agricultural products

$24 billion

14.5

Excel Maritime Carriers

Shipping

$1 billion

14.2

XOMA

Biotechnology

$455 million

-20.9

Synchronoss Technologies

Application software

$1.2 billion

53.4

You might find some of these names surprising. Drug maker Abbott Laboratories (ABT, news, msgs), for example, isn't exactly a hidden corporate name, particularly if you have rheumatoid arthritis and take its Humira for relief. But sometimes the most familiar names can mean some of the best investment opportunities, simply because we have forgotten about the potential they still hold.

Just as meaningful, the 76,000 investors on CAPS are giving these companies the nod as less obvious places to look for tomorrow's great buys. So let's delve a little deeper into why one of these companies might merit your attention.

Investors in XOMA Ltd. (XOMA, news, msgs) -- a biotech company that develops products to treat cancer, infectious diseases and immunological and inflammatory disorders -- are aware that what can be a boon to growth today can also serve to crush it tomorrow. This 26-year-old company has traded as high as the $30s (in the early 1990s) but today sports a penny-stock price below $5 a share.

Yet sales of psoriasis drug Raptiva increased 37% in the third quarter. XOMA markets the drug in collaboration with biotech giant Genentech (DNA, news, msgs). And sales of Lucentis, a treatment for age-related macular degeneration, doubled in the period. XOMA markets the drug with Genentech and Novartis (NVS, news, msgs).

Equally impressive is that drug companies such as Schering-Plough (SGP, news, msgs) have decided to expand collaborations with XOMA, which seems to underscore the validity of the Berkeley, Calif., company's R&D program.

It's the expanded deals that have CAPS investors like "Stormstocker" seeing the stock's potential to outperform.

Stock Chart (Year)

XOMA
Graphical chart for XOMA
"Antibody (therapies) that are now licensed to several drug companies, like Pfizer (PFE, news, msgs), etc. . . . This is a growth-stock play on gut feeling alone. Sales . . . no earnings yet, but (theirs) is a more (natural) way to attack cancers, macular degeneration etc. using the blood's natural healing processes (attack cells, antibodies) that go after the (diseased) cells of the body/blood, killing and sweeping out the bad-guy cells," Stormstocker wrote. "Will it work? The drug companies that are licensing their (knowledge) think so . . . so why not me?"

New opportunities, expanded agreements and newly profitable -- XOMA might just be ready to zoom.

That's the bullish word on XOMA, but do you agree? Are these four-star stocks still investment-grade material? You can offer your input on CAPS. Your views can ultimately influence how the stocks are rated. Your opinion counts.

This article was reported and written by Rich Duprey for The Motley Fool. At the time of publication, he owned none of the stocks mentioned.

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